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Page 1
Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis.
Cancer Discov. 2022 Dec 2;12(12):2763-2773. doi: 10.1158/2159-8290.CD-22-0086.
Cancer Discov. 2022.
PMID: 36169447
Free PMC article.
Oncostatin M is a Master Regulator of an Inflammatory Network in Dnmt3a -Mutant Hematopoietic Stem Cells.
Schwartz LS, Young KA, Stearns TM, Boyer N, Mujica KD, Trowbridge JJ.
Schwartz LS, et al. Among authors: young ka.
bioRxiv [Preprint]. 2023 Jul 12:2023.07.12.548764. doi: 10.1101/2023.07.12.548764.
bioRxiv. 2023.
PMID: 37502912
Free PMC article.
Preprint.
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Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells.
Schwartz LS, Young KA, Stearns TM, Boyer N, Mujica KD, Trowbridge JJ.
Schwartz LS, et al. Among authors: young ka.
Exp Hematol. 2024 Feb;130:104131. doi: 10.1016/j.exphem.2023.11.005. Epub 2023 Nov 23.
Exp Hematol. 2024.
PMID: 38000729
Free article.
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Variation in Mesenchymal KITL/SCF and IGF1 Expression at Middle Age Underlies Steady-State Hematopoietic Stem Cell Aging.
Young KA, Telpoukhovskaia MA, Hofmann J, Mistry JJ, Kokkaliaris K, Trowbridge JJ.
Young KA, et al.
Blood. 2024 Apr 10:blood.2024024275. doi: 10.1182/blood.2024024275. Online ahead of print.
Blood. 2024.
PMID: 38598841
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Mesenchymal Stromal Cell Senescence Induced by Dnmt3a -Mutant Hematopoietic Cells is a Targetable Mechanism Driving Clonal Hematopoiesis and Initiation of Hematologic Malignancy.
Mistry JJ, Young KA, Colom Díaz PA, Maestre IF, Levine RL, Trowbridge JJ.
Mistry JJ, et al. Among authors: young ka.
bioRxiv [Preprint]. 2024 Mar 30:2024.03.28.587254. doi: 10.1101/2024.03.28.587254.
bioRxiv. 2024.
PMID: 38585779
Free PMC article.
Preprint.
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